The point of V.A.N.I.T.A.S is not the loss of meaning.
It is rather characteristic of history. That means the letters are arranged by the artist. In some way.
Whether it holds common meaning or the meaning to the artist.
So VANITAS. Or perhaps VANITSA?
But finally, as i started saying, the point is whatever the artist leaves behind, he has no influence over the posterity. The institution places an arte povera object on a white pedestal in a white cube space in some smart location or whatsover and so is the inevitability and brutality of history.